Cholesterol-Lowering Drug Reduces Risk Before Heart Problems Arise

The Centers for Disease Control and Prevention (CDC) notes that approximately 86 million American adults are grappling with high cholesterol. Yet, only about half are receiving medicinal treatment to lower it. An astounding new study at the Cleveland Clinic suggests that initiating cholesterol-lowering therapy ahead of heart complications can dramatically minimize the risk of heart-related ailments and death in high-risk individuals.

The research, led by Steven E. Nissen, MD, Chief Academic Officer of the Heart Vascular & Thoracic Institute at Cleveland Clinic, reveals that the drug can benefit even high-risk patients.  

Our findings indicate that individuals with high cholesterol, including statin-intolerant patients, experienced a substantial risk reduction when treated with Bempedoic Acid. This medication not only curbs LDL cholesterol but also mitigates inflammation.

For this study, Dr. Nissen's team undertook a secondary analysis of the CLEAR Outcomes trial data, investigating the efficacy of the cholesterol-lowering drug Bempedoic Acid in people intolerant to statins. The study concentrated on a pool of 4,200 people with high cholesterol and accompanying heart risk factors, such as diabetes, but who had not yet endured a heart-related incident.

Major Heart Events Reduced

The participants were administered either Bempedoic Acid or a placebo. The findings were noteworthy: following six months of treatment, Bempedoic Acid had slashed LDL or 'bad' cholesterol by 23%. 

Furthermore, the occurrence of major heart events dropped by 30%, and there was a 39% reduction in death resulting from heart disease.

Dr. Nissen underscores the importance of this study, accentuating the urgency of addressing high cholesterol before it spirals into serious heart complications. 

Patients with high cholesterol and accompanying risk factors are grossly undertreated in the United States. Only about half of them are currently receiving cholesterol-lowering drugs, such as statins.

Dr. Nissen explains that the crucial takeaway is it's critical not to leave high cholesterol untreated just because someone hasn't yet had a heart-related incident.

Individuals with risk factors must consult their health care providers to evaluate if they could benefit from cholesterol-lowering medication. It could be a statin, or it could be Bempedoic Acid.

Dr. Nissen advises those diagnosed with high cholesterol but not currently on cholesterol-lowering medication to seek counsel from their healthcare provider. The complete results of this groundbreaking study are published in the Journal of the American Medical Association.

Cholesterol Impacts Health in Several Ways

Cholesterol management is integral to maintaining overall health, and it becomes increasingly important as we age. Cholesterol, a type of fat found in our bloodstream and cells, is crucial for bodily functions such as building new cells, insulating nerves, and producing hormones. However, an imbalance in cholesterol levels, particularly high levels of low-density lipoprotein (LDL) or 'bad' cholesterol and low levels of high-density lipoprotein (HDL) or 'good' cholesterol, can lead to health complications, primarily cardiovascular disease.

As we age, our bodies tend to process cholesterol less efficiently, leading to its accumulation in the blood vessels. This build-up can form plaques that narrow or block blood flow, causing conditions like atherosclerosis. Blocked blood flow to the heart or brain can result in heart attacks or strokes, respectively, which are among the leading causes of death in older adults. Therefore, managing cholesterol levels is crucial in preventing these life-threatening events.

Also, high cholesterol levels have been linked to other health issues that are more prevalent with age. For instance, research suggests a connection between high cholesterol and the development of Alzheimer's disease and other forms of dementia. Elevated cholesterol levels in middle age may also increase the risk of developing Parkinson's disease later in life. These health issues also lead to a higher risk of long-term care as someone ages.

Lifestyle Modifications Don’t Always Work

Lifestyle changes can play a significant role in managing cholesterol levels. Regular physical activity, a healthy diet low in saturated and trans fats, and maintaining a healthy weight are all essential in managing cholesterol levels. However, lifestyle modifications may not always be sufficient, especially in older adults with other co-existing health conditions. In such cases, cholesterol-lowering medications, like statins or Bempedoic Acid, can be critical in effectively managing cholesterol levels.

It is also important to regularly monitor cholesterol levels, especially as we age. Regular health check-ups and blood tests can detect any abnormal rise in cholesterol levels early, allowing for timely intervention and treatment. Ultimately, the aim is to maintain a healthy balance of cholesterol in the body to ensure an active and disease-free life in our golden years.

Prepare and Manage Aging, Health and Finances

Remember, even though you can't control aging, you can control your lifestyle and behavior. Stay active, eat healthily, get regular check-ups, and adhere to prescribed treatments, if any. Managing cholesterol is not just about living longer; it's about living healthier and better, especially in our older years.

Regular health check-ups become increasingly critical as we age, particularly after hitting the age of 50. These medical appointments serve as preventative measures, allowing early detection of potential health issues such as high cholesterol, diabetes, or cancer. 

Identifying these conditions early can initiate appropriate treatment promptly, increasing the likelihood of better health outcomes. Alongside maintaining good health, planning for potential long-term care needs during retirement is equally crucial. 

Long-Term Care Insurance can be a pivotal part of this planning process. It provides coverage for a range of services and supports for individuals who may develop chronic medical conditions, disabilities, or cognitive impairment. By integrating regular health check-ups and securing Long-Term Care Insurance into your retirement strategy, you are proactively managing both your present and future health and financial well-being.